For endemic diseases, an outbreak occurs when incidence rises above the normally expected level. An outbreak is defined as the occurrence of more cases of disease than expected in a given area or among a specific group of people, over a given period of time. The vaccine must protect against a disease that has the potential to cause an outbreak.The vaccine must be an age-appropriate vaccine, as recommended by the Advisory Committee on Immunization Practices (ACIP) for the general US population.The Centers for Disease Control and Prevention (CDC) has specific criteria to determine which vaccines applicants for a United States Immigrant Visa (hereafter referred to as applicants) are required to show proof of having received. Overview of Vaccination Technical Instructions
